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Image Search Results
Journal: Molecular Autism
Article Title: The activation of mGluR4 rescues parallel fiber synaptic transmission and LTP, motor learning and social behavior in a mouse model of Fragile X Syndrome
doi: 10.1186/s13229-023-00547-4
Figure Lengend Snippet: Enhanced SV docking of Fmr1 KO synapses and lack of an effect of isoproterenol. Isoproterenol (100 µM, 10 min) increases SV docking in WT ( a, c, d ) but not in Fmr1 KO ( e, g, h ) PF-PC synapses. Isoproterenol induces an increasing trend in the number of docked vesicles (0–10 nm) in WT ( a ) (n = 250/3 and 203/3 synapses/mice: P = 0.059) at the expense of SVs within 10–20 nm, which decreased in number (*** P < 0.001). These changes are absent in Fmr1 KO slices ( e ) (n = 238/4 and 224/4 synapses/mice, 0–10 nm: P = 0.997; 10–20 nm: P = 0.988). Note the increase in SV at 10–20 nm in Fmr1 KO control as opposed to WT control slices ( ## P < 0.01). c, d, g, h Electron microscopy of PF-PC synapses. (B,F) The effect of isoproterenol on the SV distribution: WT (0–5 nm: *** P < 0.001); Fmr1 KO (0–5 nm: P > 0.05). Fmr1 KO control vs WT control at 0–5 nm ( ## P < 0.01). ( i ), Active Zone (AZ) length of WT (n = 250) and Fmr1 KO (n = 238) synapses ( P > 0.05). The values represent the mean ± S.E.M. Scale bar in ( c, d, g, h ) 100 nm. Generalized Linear Mixed Models (GLMM) with genotype and treatment as fixed effects, and animal subject as a random effect. P-values for fixed effects and their interactions were obtained with type II Wald Chi-Square tests and post-hoc tests were adjusted with the Tukey HSD method ( a, b, e, f ) and unpaired student’s t test in ( i ). n is the number of synapses, many synapses were analyzed per slice and several slices per mice
Article Snippet: P-values for fixed effects and their interactions were obtained with
Techniques: Control, Electron Microscopy
Journal: Ecology and Evolution
Article Title: Desiccation limits recruitment in the pleometrotic desert seed‐harvester ant Veromessor pergandei
doi: 10.1002/ece3.7039
Figure Lengend Snippet: Effect of water level on: (A) queen survival, (B) queen wet mass, (C) queen water mass, (D) queen dry mass, and (E) number of brood (larvae, pupae, and workers) produced by single queens of the seed‐harvester ant Veromessor pergandei . Values are means + 1 SE . Within each panel, significant differences across moisture levels are indicated by the letters a‐b: a > b. Groupings are based on (A) a Wald chi‐square statistic (see text) or (B–E) a one‐way ANOVA followed by Duncan's multiple range test. Note that the one‐way ANOVA in panel D was not significant ( p = 0.08), while Duncan's multiple range test was significant ( p < 0.05). Initial sample size for each treatment is given in panel A; number of queens that survived to the end of the experiment (panels B–E) is given in panel B. ND = no data as no queens survived this treatment
Article Snippet: Strength of the grouping effect can be assessed across water levels using the maximum
Techniques: Produced
Journal: Ecology and Evolution
Article Title: Desiccation limits recruitment in the pleometrotic desert seed‐harvester ant Veromessor pergandei
doi: 10.1002/ece3.7039
Figure Lengend Snippet: Percent survival for queens of the seed‐harvester ant Veromessor pergandei in the two‐factor bottle experiment (three queen numbers by three water levels). Significant differences across treatment cells are indicated by the letters a‐d: a > b > c > d. Groupings are based on the Wald chi‐square statistic (see text). Sample size per treatment cell; n = 120 queens for 0 and 5 mls water, n = 60 queens for 10 mls water
Article Snippet: Strength of the grouping effect can be assessed across water levels using the maximum
Techniques: